Ukuphumelela Okubalulekile
Ngomhla zingama-28 kuMfumfu, ubuchwepheshe obuqondile bokusebenzisa i-deamination functionalization yama-amine anamakha obuthuthukiswe ithimba lika-Zhang Xiaheng ovela e-Hangzhou Institute for Advanced Study, i-University of Chinese Academy of Sciences (HIAS, UCAS) yashicilelwa kuMvelo. Lobu buchwepheshe buxazulula izinselelo zokuphepha nezindleko ezikhungethe imboni yamakhemikhali iminyaka engu-140.
Amaphuzu Avelele Ezobuchwepheshe
1.Ilahla inqubo kasawoti ye-diazonium yendabuko (ejwayele ukuqhuma kanye nokungcola okuphezulu), ukufeza ukuguqulwa okuphumelelayo kwebhondi ye-CN ngokusebenzisa i-N-nitroamine intermediates.
2.Ayidingi ama-catalysts ensimbi, inciphisa izindleko zokukhiqiza ngo-40% -50%, futhi isiqedile ukuqinisekiswa kwe-kilogram-scale.
3.Isebenza cishe kuwo wonke ama-amine e-heteroaromatic amakhemikhali kanye nokuphuma kwe-aniline, ngaphandle kokuvinjelwa indawo yeqembu lama-amino.
Umthelela Wezimboni
1.Imboni yezemithi: Njengohlaka lwamathambo oluyisihluthulelo lwama-70% emithi ye-molecule encane, ukuhlanganiswa kwemithi elwa nomdlavuza kanye nama-antidepressants kuba okuphephile futhi ukonga kakhulu. Amabhizinisi afana ne-Baicheng Pharmaceutical kulindeleke ukuthi anciphise izindleko ngo-40% -50%.
2.Imboni ye-Dyestuff: Amabhizinisi ahamba phambili njenge-Zhejiang Longsheng, anesabelo semakethe esingu-25% kuma-amine anephunga elimnandi, axazulula ingozi yokuqhuma osekukhawule isikhathi eside ukunwetshwa kwamandla.
3.Imboni yezibulala-zinambuzane: Amabhizinisi afaka i-Yangnong Chemical azothola ukwehliswa okukhulu kwezindleko zezibulala-zinambuzane.
I-4.Izinto ze-elekthronikhi: Ikhuthaza ukuhlanganiswa okuluhlaza kwezinto zokusebenza ezikhethekile.
I-Capital Market Reaction
Ngomhla zi-3 kuNovemba, imboni yamakhemikhali yaqina ngokumelene nethrendi yemakethe, nengxenye ye-amine enephunga elimnandi ehola izinzuzo kanye namasheya ahlobene nawo abonisa amandla aphelele.
Isikhathi sokuthumela: Nov-06-2025